GLYCOCONJUGUÉS ANTICORPS-MÉDICAMENT SPÉCIFIQUES D'UN SITE ET PROCÉDÉS

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专利权人:

University Of Georgia Research Foundation; Inc.

发明人:

申请号：

EP15776105.7

公开号：

EP3129402A4

申请日:

2015.04.08

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Compounds, compositions, and methods are provided for covalently linking an antibody or an antibody fragment to a cargo molecule, such as a therapeutic or a diagnostic agent, using a combination of enzymatic glycan remodeling and click chemistry. The method allows a cargo molecule to be selectively and efficiently attached post-translationally to an antibody or an antibody fragment. Also provided are antibody drug conjugates, methods of making, and uses thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/