The present invention provides monoclonal antibodies, or antigen-binding fragments thereof, that bind to the influenza hemagglutinin (HA) protein, pharmaceutical compositions comprising the antibodies and methods of use. The antibodies of the invention are useful for inhibiting or neutralizing influenza virus activity, thus providing a means of treating or preventing influenza infection in humans. In some embodiments, the invention provides for use of one or more antibodies that bind to the influenza HA for preventing viral attachment and/or entry into host cells. The antibodies of the invention may be used prophylactically or therapeutically and may be used alone or in combination with one or more other anti-viral agents or vaccines.本發明提供結合至流行性感冒血球凝集素(HA)蛋白的單株抗體或其抗原結合片段、包含該等抗體的醫藥組成物及使用方法。本發明抗體可用於抑制或中和流行性感冒病毒活性,因而提供一種在人類體內治療或預防流行性感冒感染的方法。在一些具體例中,本發明提供結合至流行性感冒HA之一或多種抗體供預防病毒附接及/或進入宿主細胞中的用途。本發明抗體可預防性地或治療性地使用且可單獨使用或與一或多種其他抗病毒藥劑或疫苗組合使用。
