Susana Fiorentino,John Fredy Hernandez,Claudia Uruena,Diana Castaneda,Luis Miguel Pombo,Tito Alejandro Sandoval
申请号:
US14427552
公开号:
US09931355B2
申请日:
2012.09.11
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to a combination of compounds derived from gallic acid, with an antitumoral and antimetastatic activity via a mechanism that involves the induction of apoptosis and the immunogenic death of the tumor cells and the subsequent activation of the specific immune response. The invention also relates to a composition containing a combination of derivatives of gallic acid and pharmaceutically acceptable excipients for the production of useful medicaments in the treatment of cancer. The invention further relates to the use of said composition in a coadjuvant in conventional chemotherapy, reducing the doses of chemotherapeutic agents used in the treatment of cancer.