UNIVERSITY OF BONN;UNIVERSITY OF RUTGERS;THE STATE UNIVERSITY OF NEW JERSEY;MEMORIAL SLOAN KETTERING CANCER CENTER
发明人:
GAU PU,GAFFNEY BARBARA L,ZILLINGER THOMAS
申请号：
AP2015008746
公开号：
AP2015008746A0
申请日:
2014.04.29
申请国别(地区):
AP
年份:
2015
代理人:
摘要：
The present disclosure provides, among other things, novel cyclic-GMP-AMP (cGAMP) analogs, mimics, mimetics and variants, and compositions and kits thereof； methods of using the compounds as described herein for treating cancer, and immune disease, disorders, or conditions； methods of using the compounds as described herein for modulating cGAS and STING； and methods of designing or characterizing a cGAS modulator.
