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Sustained release formulations using non-aqueous carriers
专利权人:
ASTRAZENECA PHARMACEUTICALS LP
发明人:
HOUCHIN MARY L,LEE ROBIN H,QI HONG,OEHRTMAN GREG,JENNINGS ROBERT N,COLEMAN SCOTT H
申请号:
NZ60499709
公开号:
NZ604997A
申请日:
2009.09.04
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
The disclosure relates to a manufactured pre-mixed formulation for injection consisting essentially of a suspension of: (i) a pharmaceutically acceptable non-aqueous carrier which consists essentially of one or more triglycerides of C6-C12 fatty acids and (ii) microspheres which consist essentially of a poly(lactide-co-glycolide) polymer having dispersed therein about 5% (w/w) exenatide as active pharmaceutical ingredient and about 2% (w/w) sucrose wherein the ratio of lactide:glycolide in the polymer is about 1:1.
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