ПЕРЛРОТ Д. Виктор (US),ТО Ва Юань (US),ЛЯН Хун (US)
申请号：
RU2018126519
公开号：
RU2018126519A
申请日:
2016.12.29
申请国别(地区):
RU
年份:
2020
代理人:
摘要：
Provided herein are anti-VEGF-A antibodies and antibody conjugates thereof. Some embodiments of the antibodies can be conjugated to a moiety, such as a HEMA-PC polymer. Some embodiments of the antibody conjugates can retain or enhance antibody activity. The antibody and conjugate thereof can be particularly useful for treating diabetic retinopathy. Further provided are methods for conjugation of a polymer to a protein such as an antibody, such as IgG1.
