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PRODUCTION OF IL-37 IN PLANTS
专利权人:
PRAIRIE PLANT SYSTEMS INC.
发明人:
MA, SHENGWU,JEVNIKAR, ANTHONY,DOSHI, KETAN M.,LOUKANINA, NATALIA N.,POLLOCK, BRENT R.,HOLBROOK, LARRY A.,ARNISON, PAUL G.
申请号:
CA2901370
公开号:
CA2901370A1
申请日:
2015.08.24
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Described herein is the production, recovery and purification of humaninterleukin 37from plants. The invention relates to methods of molecular farming plant,including intobacco, Tarwi and Oca, wherein both stable and transient expression of thefive knownvariants of human interleukin 37 were made IL-37 variants are additionallyproduced asfusions with soybean lectin, transferrin and polyhistidine tags to aid instability and recoveryby affinity chromatography.
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