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POLYTHERAPIE POUR TRAITER UN CANCER
专利权人:
LIMITED;DAIICHI SANKYO COMPANY
发明人:
SEKI, TAKAHIKO
申请号:
CA2976752
公开号:
CA2976752C
申请日:
2016.02.19
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
It is intended to provide a medicament and a methodfor treating cancer comprising a compound having MDM2inhibiting activity and a compound having FLT3 inhibitingactivity in combination. The present invention providesa medicament comprising (3'R,4'S,5'R)-N-[(3R,6S)-6-carbamoyltetrahydro-2H-pyran-3-yl]-6"-chloro-4'-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2"-oxo-1",2"-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3"-indole]-5'-carboxamide or a pharmaceutically acceptablesalt thereof and N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea or a pharmaceutically acceptable saltthereof in combination, and a treatment method usingthese compounds or salts in combination.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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