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TREATMENT METHOD BY COMBINED USE OF MDM2 INHIBITOR AND BTK INHIBITOR
专利权人:
LIMITED;DAIICHI SANKYO COMPANY
发明人:
Takahiko SEKI
申请号:
US15566336
公开号:
US20180353493A9
申请日:
2016.04.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
It is intended to provide a medicament and a method for treating cancer comprising a compound having MDM2 inhibiting activity and a compound having BTK inhibiting activity in combination. The present invention provides a medicament comprising (3′R,4′S,5′R)-N-[(3R,6S)-6-carbamoyltetrahydro-2H-pyran-3-yl]-6″-chloro-4′-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2″-oxo-1″,2″-dihydrodispiro[cyclohexane-1,2′-pyrrolidine-3′,3″-indole]-5′-carboxamide or a pharmaceutically acceptable salt thereof and ibrutinib or a pharmaceutically acceptable salt thereof in combination, and a treatment method using these compounds or salts in combination.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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