Barbour, Robin,Games Thiel, Kate Dora,Nijjar, Tarlochan S.
申请号：
AU2013329381
公开号：
AU2013329381A1
申请日:
2013.10.08
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The invention provides monoclonal antibody 5C1 and related antibodies. The 5C1 antibody binds to an epitope within residues 118-126 of α-synuclein. The antibodies of the invention are useful, for example, for treating and/or diagnosing disorders associated with α-synuclein, particularly accumulation of α-synuclein deposits. Such disorders include Lewy body diseases, such as Parkinsons disease, Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimers disease (LBV), Combined Alzheimers and Parkinson disease, pure autonomic failure and multiple system atrophy (MSA).
