PROBLEM TO BE SOLVED: To provide a novel and useful kinesin inhibitor and a composition useful for alleviating and suppressing various pigmentation symptoms such as stains and freckles.SOLUTION: This invention provides a kinesin inhibitor or pigmentation inhibitor comprising specific material, namely caffeic acid or caffeic acid derivative (caffeic acid or chlorogenic acid) as an active ingredient. Further, this invention provides various compositions comprising the kinesin inhibitor or pigmentation inhibitor (a pharmaceutical composition, a food and drink composition, or a cosmetic composition).COPYRIGHT: (C)2015,JPO&INPIT【課題】新規で有用なキネシン抑制剤及び、シミやソバカスをはじめとする様々な色素沈着症状の緩和、抑制に有用な組成物を提供する。【解決手段】特定の物質、カフェ酸又はカフェ酸誘導体(カフェ酸、クロロゲン酸)を有効成分として含有するキネシン抑制剤又は色素沈着抑制剤。更に、キネシン抑制剤又は色素沈着抑制剤を含有する各種組成物(医薬組成物、飲食品組成物、化粧料組成物)を提供する。【選択図】なし