Bin Yang,Jason Grant Kettle,Thomas George Christopher Hayhow,Timothy Gordon Rasmusson,Johannes Wilhelmus Maria Nissink,Charlene Fallan,Gillian McGregor Lamont
申请号：
US16223224
公开号：
US10519152B2
申请日:
2018.12.18
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The specification generally relates to compounds of Formula (I):and pharmaceutically acceptable salts and prodrugs thereof, where R1, R4, R5, R6, R7, Linker, X, Y, A, G, D and E have any of the meanings defined herein. This specification also relates to the use of such compounds and pharmaceutically acceptable salts and prodrugs thereof in methods of treatment of the human or animal body, for example in prevention or treatment of cancer. This specification also relates to processes and intermediate compounds involved in the preparation of such compounds and to pharmaceutical compositions containing them.
