STEVEN R.;BUCHANAN, CATRIONA L.;HOLGATE, ROBERT G.;LEDBETTER;DUNCAN, ALEXANDER R.;FINCH, DONNA K.;JERMUTUS, LUTZ U.;LEDBETTER, STEVEN R.;HART, CELIA P.
发明人:
LEDBETTER, STEVEN R.,HART, CELIA P.,HOLGATE, ROBERT G.,JERMUTUS, LUTZ U.,BUCHANAN, CATRIONA L.,DUNCAN, ALEXANDER R.,FINCH, DONNA K.
申请号：
CA2597098
公开号：
CA2597098C
申请日:
2006.02.08
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates to antibody molecules, in particular antibodymolecules that bind Transforming Growth Factor beta (TGF.beta.), and usesthereof. More particularly, the invention relates to antibody molecules thatbind and preferably neutralise TGF.beta.1, TGF.beta.2, and TGF.beta.3, so-called "pan-specific" antibody molecules, and uses of such antibody molecules.Preferred embodiments within the present invention are antibody molecules,whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments(e.g. scFv, Fab, dAb).
