LEDBETTER Steven R.,HART Celia P.,HOLGATE Robert G.,JERMUTUS Lutz U.,BUCHANAN Catriona L.,DUNCAN Alexander R.,FINCH Donna K.
申请号：
SI200632315
公开号：
SI1850873T1
申请日:
2006.02.08
申请国别(地区):
SI
年份:
2019
代理人:
摘要：
The present invention relates to antibody molecules, in particular antibody molecules that bindransformingrowthactor beta (TGFβ) and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGFβ1, TGFβ2, and TGFβ3, so-called 'pan-specific' antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).
