Steven R. Ledbetter,Celia Patricia Hart,Robert G. Holgate,Lutz U. Jermutus,Catriona L. Buchanan,Alexander R. Duncan,Donna K. Finch
申请号：
US16197802
公开号：
US10781252B2
申请日:
2018.11.21
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGFβ), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGFβ1, TGFβ2 and TGFβ3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).
