TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA

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专利权人:

JACOB ARY FLOHIL

发明人:

JACOB ARY FLOHIL

申请号：

NL2020004

公开号：

NL2020004B1

申请日:

2017.12.01

申请国别(地区):

NL

年份:

2018

代理人:

摘要：

The present invention relates to an inhibitor of MELK and/or ROR2, preferably for use in the treatment of diffuse intrinsic pontine glioma (DIPG), wherein said DIPGis preferably characterized by Overexpression of MELK and/or Overexpression of ROR2. The inhibitor may be combined with a P-glycoprotein inhibitor, an Abcb1 a inhibitor, Abcb1 b inhibitor, mannitol, or an Abcg2 inhibitor.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/