TRAITEMENT DU GLIOME PONTIQUE INTRINSEQUE DIFFUS

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专利权人:

JACOB ARY;FLOHIL

发明人:

FLOHIL, JACOB ARY

申请号：

CA3080488

公开号：

CA3080488A1

申请日:

2017.12.08

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present invention relates to an inhibitor of MELK and/or ROR2, preferably for use in the treatment of diffuse intrinsic pontine glioma (DIPG), wherein said DIPG is preferably characterized by overexpression of MELK and/or overexpression of ROR2. The inhibitor may be combined with a P-glycoprotein inhibitor, an Abcb1a inhibitor, Abcb1b inhibitor, mannitol, or an Abcg2 inhibitor.

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中国工程科技知识中心

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