Xianshuang Liu,Zhenggang Zhang,Michael Chopp,Lei Wang
申请号:
US14761442
公开号:
US09670490B2
申请日:
2014.01.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Some embodiments comprise methods, systems, and compositions to promote, improve and/or increase neuronal differentiation, oligodendrocyte differentiation, or neurological outcome or function in a patient in need thereof. Some embodiments also comprise the administration a composition comprising a pharmaceutically effective amount of one or more of a group comprising microRNA-146a, a promoter of microRNA-146a expression, a microRNA-146a mimic, thymosin beta 4, and a phosphodiesterase 5 inhibitor to treat neurological conditions, disease, or injury in mammals, including in human beings.