FORMULATIONS DE FULVESTRANT ET METHODES D'UTILISATION DE CELLES-CI

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专利权人:

INC.;EAGLE PHARMACEUTICALS

发明人:

CHEN, FENG-JING,KRILL, STEVEN L.,SHMEIS, RAMA ABU

申请号：

CA3022834

公开号：

CA3022834A1

申请日:

2017.05.05

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The disclosure is directed to fulvestrant formulations including suspensions of fulvestrant particles suitable for injection. The formulations can comprise fulvestrant particles having an LD Dv(10) less than about 3 microns, for example, between about 1 micron to about 3 microns, an LD Dv(50) less than about 35 microns, for example, between about 2 microns and about 35 microns, and an LD Dv(90) less than about 120 microns, for example, between about 4 microns and about 120 microns. The formulations can comprise fulvestrant particles having a CE Dv(90) less than about 200 microns, for example, between about 10 microns and about 200 microns, a CE Dv(50) less than about 60 microns, for example, between about 5 microns and about 60 microns, and a CE Dv(10) less than about 25 microns, for example, between about 1 micron and about 25 microns.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/