Tarik Soliman,Laura M. Hales,Daniel B. Hall,Christopher So,Howard P. Sard,Vishnumurthy Hegde
申请号:
US15430449
公开号:
US20170216449A1
申请日:
2017.02.11
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides non-hormonal vitamin D conjugated to apelin proteins that result in increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. In some embodiments, the vitamin D targeting groups are coupled to the apelin proteins via the third carbon on the vitamin D backbone.