Tarik Soliman,Laura M. Hales,Daniel B. Hall,Howard P. Sard,Vishnumurthy Hegde
申请号：
US14919671
公开号：
US09789197B2
申请日:
2015.10.21
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention provides non-hormonal vitamin D conjugated to therapeutic RNA compounds that result in the compounds having increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. The vitamin D targeting groups are coupled to the therapeutic RNA compounds via the third carbon on the vitamin D backbone.
