BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
发明人:
SPUDICH, JOHN LEE,GOVORUNOVA, ELENA G.,SINESHCHEKOV, OLEG A.
申请号:
CA2979975
公开号:
CA2979975A1
申请日:
2016.03.18
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Methods and compositions used to identify and characterize a new class of rhodopsins derived from algae, which are highly sensitive and efficient anion- conducting channelrhodopsins. The rhodopsin domain of these anion-conducting channelrhodopsins have been cloned and expressed in mammalian systems and thus may be used in, among others, optogenetic applications and as therapeutic agents for electrically active cell mediated disorders.