Chi B. Vu;Charles Blum;Lauren McPherson;Pui Yee Ng;Mohammed Mahmood Ahmed;Robert B. Perni;Jeremy S. Disch
发明人:
Pui Yee Ng,Charles Blum,Lauren McPherson,Robert B. Perni,Chi B. Vu,Mohammed Mahmood Ahmed,Jeremy S. Disch
申请号：
US13504134
公开号：
US09556201B2
申请日:
2010.10.29
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
