Ng, Pui Yee,Blum, Charles,McPherson, Lauren,Perni, Robert B.,Vu, Chi B.,Ahmed, Mohammed Mahmood,Disch, Jeremy S.
申请号:
AU2010319842
公开号:
AU2010319842A1
申请日:
2010.10.29
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.