The present invention relates to a selective dual delta (d) and gamma () PI3K protein kinase modulator (S) N (5 (4 amino 1 (1 (5 fluoro 3 (3 fluorophenyl) 4 oxo 4H chromen 2 yl)ethyl) 1H pyrazolo[3 4 d]pyrimidin 3 yl) 2 methoxyphenyl) methane sulfonamide methods of preparing them pharmaceutical compositions containing them and methods of treatment prevention and/or amelioration of PI3K kinase mediated diseases or disorders with them.