Федеральное государственное бюджетное учреждение "Федеральный центр охраны здоровья животных" (ФГБУ "ВНИИЗЖ") (RU)
发明人:
Куляшбекова Шамшагуль Куляшбековна (RU),Пяткина Алла Александровна (RU),Курненкова Елена Викторовна (RU)
申请号：
RU2012130979/10
公开号：
RU2012130979A
申请日:
2012.07.19
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. Trivalent culture kpetochno-associated virusvaktsina against BM "Trimarek", comprising a mixture of intracellular Mareks disease virus (EBM), chicken herpes virus (WMC), herpes virus of turkeys (VGI), serum bovine (cattle) and dimethylsulfoxide (DMSO ) as the tread, characterized in that it as the antigenic material comprises a slurry SPF chicken embryos fibroblasts (CEF) infected with the three virus serotypes BM, namely nonpathogenic strain "3004" VBM, natural and attenuated nonpathogenic strain "the SB-1" SHAPE, nonpathogenic antigenically related strains "Vladimir" WGI taken to effectively sootnoshenii.2. Virusvaktsina according to claim 1, characterized in that it contains antigenic material from a nonpathogenic strain "3004" VBM produced in cell culture by the FEC as a cell suspension with an infectious activity of not less than 5.0 × 10FOE / cm, at 20 ÷ 25 wt.%. 3. Virusvaktsina according to claim 1, characterized in that it contains antigenic material of natural and non-pathogenic attenuated strain «SB-1" SHAPE resultant culture FEC cells into cell suspension with infectious activity not lower than 1,0 × 10FOE / cm in an amount of 10 ÷ 15 wt.%. 4. Virusvaktsina according to claim 1, characterized in that it contains antigenic material of antigenically-related nonpathogenic strain "Vladimir" VGI resultant culture FEC cells into cell suspension with infectious activity not lower than 1,0 · 10FOE / cm, in an amount 30 ÷ 35 wt.%. 5. Virusvaktsina according to claim 1, characterized in that it comprises a blood serum of cattle in an amount of 15 ÷ 25 wt.%. 6. Virusvaktsina according to claim 1, characterized in that it contains DMSO as a cryoprotectant in an amount of 10 ÷ 151. Трехвалентная культуральная кпеточно-ассоциированная вирусвакцина против БМ «Тримарек», содержащая смесь внутриклеточного вируса болезни Марека (ВБМ), вируса герпеса кур (ВГК), вируса герпеса индеек (ВГИ), сыворотку крови крупного рогатого скота (КРС) и диметилсульфоксид (ДМСО) в качест
