ANDREASEN LARS VIBE,WOOD GRITH KRØYER,CHRISTENSEN DENNIS
申请号:
IN3/DELNP/2014
公开号:
IN2014DN00003A
申请日:
2014.01.01
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The invention discloses a method for the formation of liposomes by using high shear mixing of aqueous solution of lipid powder the lipid powder can be produced by any known technique. Components of the liposomes include but are not limited to cationic lipids immunostimulators/immunopotentiators and macromolecules as components for the liposome formation. The disclosed method describes the formulation of stable liposomes solitary or complexing high concentrations of macromolecules such as proteins DNA and RNA having opposite charge of the liposomes by high shear mixing where aggregation is avoided due to the formulation method.