Joyce Gonzales;Alexander D. Verin;Umapathy N. Siddaramappa
发明人:
Umapathy N. Siddaramappa,Alexander D. Verin,Joyce Gonzales
申请号：
US13603913
公开号：
US20120329860A1
申请日:
2012.09.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides methods for treating inflammation in the lungs of a subject in need of such treatment, comprising the step of administering an effective amount of a composition comprising b-nicotinamide adenine dinucleotide to the subject. Also provided is a method of increasing integrity of a vascular barrier in a subject, comprising the step of contacting one or both of human P2Y1 receptors or P2Y11 receptors in the subject with an amount of a composition comprising beta-nicotinamide adenine dinucleotide effective to activate the receptors； wherein activation thereof increases the integrity of the vascular barrier in the subject.
