METHOD OF GENERATING TUMOR-SPECIFIC T CELLS

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专利权人:

发明人:

Julian Kim,Kevin Choong,Hallie Graor,Mei Zhang,John Ammori,Anthony Visioni

申请号：

US15954274

公开号：

US20180228844A1

申请日:

2018.04.16

申请国别(地区):

US

年份:

2018

代理人:

摘要：

A method of treating cancer in a subject includes contacting an enriched population of T-cells obtained from cancer or tumor draining lymph nodes ex-vivo with: an anti-CD3 antibody, an anti-CD28 antibody, and/or functional fragments thereof, and optionally a VEGF inhibitor and/or an IL-2 receptor agonist, at amounts effective to activate and expand the T-cells and administering the activated and expanded T-cells to the subject.

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中国工程科技知识中心

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http://www.ckcest.cn/home/