Method of generating tumor-specific T cells

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专利权人:

发明人:

Julian Kim,Hallie Graor,Mei Zhang,Anthony Visioni

申请号：

US14205069

公开号：

US09944898B2

申请日:

2014.03.11

申请国别(地区):

US

年份:

2018

代理人:

摘要：

A method for the expansion of tumor-specific T-cells includes obtaining an enriched population of T-cells from a subject with cancer and contacting the enriched population of T-cells ex-vivo with: (i) an anti-CD3 antibody, an anti-CD28 antibody, and/or functional fragments thereof, and (ii) a VEGF inhibitor, to activate and expand the T-cells.

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