Antibodies that bind to c-Met are provided herein, as well as related compositions and methods of use. Methods of use encompass cancer therapies and diagnostics. In certain embodiments, antibodies bind mammalian cell surface antigen (e.g., cancer cell surface antigen). The antibodies can also be endocytosed upon binding to cells. Cells that can be targeted by the antibodies include carcinomas, such as those in lung, kidney, liver, stomach, breast, and brain, etc.本發明揭露可結合至c-Met之抗體,以及相關組合物,及其使用方法。該使用方法包含癌症療法及診斷。於部分具體實施例中,抗體可結合至哺乳動物細胞表面抗原(如:癌細胞表面抗原)。該抗體亦可經結合至該細胞後被胞飲。可被該等抗體所標靶之細胞包括各種癌症,像是肺癌、腎癌、肝癌、胃癌、乳癌及腦癌等。
