GONZALEZ OJER, CARLOS,GONI ALLO, BEATRIZ,PASTOR FERNANDEZ, FIONA,YARNOZ DE MIGUEL, CAYETANA
申请号：
CA2814103
公开号：
CA2814103C
申请日:
2011.10.19
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Anhydrous topical gel composition of mupirocin or its salts comprising: a) a lipophilic base selected from the group consisting of petrolatum, medium- chain triglycerides, isopropyl myristate and mixtures thereof； b) a bioadhesive selected from the group comprising polyvinylpyrrolidone and polymethacrylates； and c) a solvent selected from the group comprising ethanol, propanol, and isopropanol； which is stable and shows an increased residence time of the active ingredient in the skin, resulting in an improved clinical effect in the treatment of bacterial skin infections while maintaining the safety profile of the commercial pharmaceutical product.
