Procedure for the preparation of (4S) - 4 - (cyano - 2-methoxyphenyl) - 5 - ethoxy - 2.8 - dimethyl - 1,4 - dihydro - 1.6 - naftiridina - 3 - carboxamide and Purified for use as pharmaceutical Active principle

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专利权人:

BAYER PHARMA AKTIENGESELLSCHAFT

发明人:

PLATZEK, Johannes

申请号：

CL2018000427

公开号：

CL2018000427A1

申请日:

2018.02.16

申请国别(地区):

CL

年份:

2018

代理人:

摘要：

The present invention relates to a novel and improved method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide of the formula (I) and of a crystalline modification of said compound.PROCEDIMIENTO PARA LA PREPARACIÓN DE (4S)-4-(4-CIANO-2-METOXIFENILO)-5-ETOXI-2,8-DIMETILO-1,4-DIHIDRO-1,6-NAFTIRIDINA-3-CARBOXAMIDA Y SU PURIFICACIÓN PARA SU USO COMO PRINCIPIO ACTIVO FARMACÉUTICO

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中国工程科技知识中心

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http://www.ckcest.cn/home/