ASPNES, GARY ERIK GE,DIDIUK, MARY THERESA MT,FILIPSKI, KEVIN JAMES KJ,GUZMAN-PEREZ, ANGEL A-,LEE, ESTHER CHENG YIN ECY,PFEFFERKORN, JEFFREY ALLEN JA,STEVENS, BENJAMIN DAWSON BD,TU, MEIHUA MIKE MM,.阿斯普內斯,.狄第烏克,.菲利普斯基,.古斯曼-佩雷斯,.李,.普費弗科恩,STEVENS, BEN
申请号：
HK15108486.7
公开号：
HK1207858A
申请日:
2014.02.28
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
