ASPNES, GARY ERIK,DIDIUK, MARY THERESA,FILIPSKI, KEVIN JAMES,GUZMAN-PEREZ, ANGEL,PFEFFERKORN, JEFFREY ALLEN,STEVENS, BENJAMIN DAWSON,TU, MEIHUA MIKE
申请号：
CA2822017
公开号：
CA2822017C
申请日:
2011.12.09
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
