Michael John Bennett,Juan Manuel Betancort,Amogh Boloor,Stephen W. Kaldor,Jeffrey Alan Stafford,James Marvin Veal
申请号：
US14517705
公开号：
US09034900B2
申请日:
2014.10.17
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.
