PROBLEM TO BE SOLVED: To provide a differentiation inducer to brown-like adipocytes of white adipocytes to develop a fundamental therapy and/or preventive which prevents and/or treats metabolic syndrome by changing properties of adipocyte itself, which is neither suppression of appetite, nor fat absorption suppression, in order to change metabolism.SOLUTION: Disclosed is a differentiation inducer to brown-like adipocyte of white adipocyte characterized by containing a cyclization reaction product or a pharmaceutically acceptable salt thereof obtained by a method of heat treatment of hydroxystilbenes under alkaline conditions.
