Process for the preparation of strontium ranelate

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专利权人:

Bobba Venkata Siva Kumar;Kosampally Srinivas;Sanjay Anantha Kale;Nitin Sharad Chandra Pradhan

发明人:

Bobba Venkata Siva Kumar,Kosampally Srinivas,Sanjay Anantha Kale,Nitin Sharad Chandra Pradhan

申请号：

US11990682

公开号：

US08624041B2

申请日:

2006.08.18

申请国别(地区):

US

年份:

2014

代理人:

摘要：

A process for the preparation of strontium ranelate or a hydrate thereof is provided comprising (a) reacting a tetraester compound of Formula II: wherein R, R1, R2, and R3 are independently a linear or branched C1-C6 alkyl group or a substituted or unsubstituted C3-C12 cyclic group, in the presence of a lithium base and in a solvent with an inorganic acid salt of strontium.

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