Contemplated compounds and compositions include boron in form of a complex with a ligand that provides for improved bioavailability and stability of the boron compound in serum. Most remarkably, contemplated compounds will retain the complex structure even during flfelr passage through the gastrointestinal system. Thus, contemplated boron complexes are delivered and measurable in serum at significant quantities upon oral administration. Moreover, complexes according to the inventive subject matter increase bone density in a vitamin D independent manner.
