Prodrug compositions, prodrug nanoparticles, and methods of use thereof

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专利权人:

The Washington University

发明人:

Lanza, Gregory M.,Pan, Dipanjan

申请号：

AU2011239414

公开号：

AU2011239414A1

申请日:

2011.04.15

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

Nanoparticles comprising a prodrug and prodrugs linked to phospholipids, wherein the linkages facilitate release of the prodrugs from the nanoparticles to sites within a target cell or cell membrane by fusion of the particle and the cell membrane are disclosed. Also disclosed are methods for producing and using the nanoparticles and their constituents.

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