A catheter for use in a fluid exchange system, including: an external catheter wall extending between a proximal end and a distal end of the catheter； a fluid column chamber at a distal region of the catheter, with the fluid column chamber including a plurality of fluid exchange apertures disposed in the external catheter wall； a first lumen in fluid communication with the fluid column chamber and adapted for aspirating fluid from the fluid column chamber； a second lumen in fluid communication with the fluid column chamber and adapted for irrigating fluid into the fluid column chamber； and a first sensor positioned to measure a fluid pressure within a fluid column of the fluid column chamber, with the first sensor disposed at a distal end of a lead, and the lead extending through a first dedicated lumen formed within the catheter or on an exterior of the catheter.
