GAVISH-GALILEE BIO APPLICATIONS LTD;HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
发明人:
PITCOVSKI, JACOB,SHAHAR, EHUD,GORODETSKY, RAPHAEL
申请号:
CA2713137
公开号:
CA2713137C
申请日:
2009.01.25
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention provides microparticles or nanoparticles for treatment of tumorscomprising: (i) a targeting agent tothe tumor or the tumor environment; and (ii) at least one inducer thatstimulates a desired immune response in the tumorenviron-ment, leading to tumor apoptosis, wherein components (i) and (ii) arenon-covalently or covalently attached to the surface of saidmicroparticles or nanoparticles. The targeting agent is an agent thatrecognizes and binds to an antigen, a receptor or other moleculesfound on the surface of tumor cells or in the tumor environment and arepreferably antibodies.