Gavish-Galilee Bio Applications Ltd;Hadasit Medical Research Services and Development Ltd.
发明人:
Pitcovski, Jacob,Shahar, Ehud,Gorodetsky, Raphael
申请号:
AU2009207287
公开号:
AU2009207287A8
申请日:
2009.01.25
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention provides microparticles or nanoparticles for treatment of tumors comprising: (i) a targeting agent to the tumor or the tumor environment; and (ii) at least one inducer that stimulates a desired immune response in the tumor environment, leading to tumor apoptosis, wherein components (i) and (ii) are non-covalently or covalently attached to the surface of said microparticles or nanoparticles. The targeting agent is an agent that recognizes and binds to an antigen, a receptor or other molecules found on the surface of tumor cells or in the tumor environment and are preferably antibodies.