(A) Active ingredient (B) Zein (C) The wax way the material, and (d) the bulking medicine or the spheroidization medicine is included, the tablet or the sustained-release constituent of poly particulate configurations is offered. This constituent chiyuaburu Characteristic and/or is an eating quality aural masking property. In addition, oral medication configuration, and this kind of constituent which include this kind of constituent are prepared and manner, and the medication configuration which are used are offered.(a)活性成分;(b)ゼイン;(c)ろう様物質、及び(d)バルキング剤又は球状化剤を含む、錠剤又は多微粒子形態の徐放性組成物を提供する。本組成物は、チュアブル性及び/又は食味マスキング特性がある。また、このような組成物を含む経口投薬形態、及びこのような組成物を調製し使用する方法、及び投薬形態を提供する。