Liangxian Cao;Donald Corson;Neil Almstead;Peter Seongwoo Hwang;Soongyu Choi;William Lennox;Zhengxian Gu;Langdon Miller;Harry H. Miao;Jason D. Graci;Y;Jeffrey Allen Campbell;Tamil Arasu;Thomas W. Davis
发明人:
Neil Almstead,Tamil Arasu,Soongyu Choi,Liangxian Cao,Jeffrey Allen Campbell,Donald Corson,Thomas W. Davis,Jason D. Graci,Zhengxian Gu,Peter Seongwoo Hwang,William Lennox,Harry H. Miao,Langdon Miller,Y
申请号：
US13321257
公开号：
US09351964B2
申请日:
2010.05.27
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Compounds, such as compounds of Formula (I), that selectively inhibit pathological production of human vascular endothelial growth factor (VEGF) and compositions comprising such Compounds are described. Compounds that inhibit viral replication or the production of viral RNA or DNA or viral protein and compositions comprising such Compounds are described. Also described are methods of reducing VEGF using such Compounds and methods for treating cancer and non-neoplastic conditions involving the administration of such Compounds. Further described are methods of inhibiting viral replication or the production of viral RNA or DNA or viral protein using such Compounds and methods for treating viral infections involving the administration of such Compounds. The Compounds may be administered as a single agent therapy or in combination with one or more additional therapies to a human in need of such treatments.
