The present invention is directed to the tosylate salt of trans-N-ethyl-3- fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)-phenyl]-cyclobutanecarboxamide (1): to solvates (e.g., hydrates) thereof, to polymorphs thereof, to pharmaceutical compositions thereof and to a method of treating depression, mood disorders, schizophrenia, anxiety disorders, cognitive disorders, Alzheimer's disease, attention-deficit disorder (ADD), attention-deficit hyperactivity disorder (ADHD), psychotic disorders, sleep disorders, obesity, dizziness, epilepsy, motion sickness, respiratory diseases, allergy, allergy-induced airway responses, allergic rhinitis, nasal congestion, allergic congestion, congestion, hypotension, cardiovascular disease, diseases of the GI tract, hyper- and hypo-motility and acidic secretion of the gastro-intestinal tract comprising administering a therapeutically effective amount thereof.本發明係關於一種反-N-乙基-3-氟-3-[3-氟-4-(吡咯啶-1-基甲基)-苯基]-環丁烷甲醯胺(1)之甲苯磺酸鹽：其溶劑合物(例如，水合物)、其多晶型物、其醫藥組合物及一種治療以下病症之方法：抑鬱症、情感障礙、精神分裂症、焦慮症、認知病症、阿茲海默氏病(Alzheimer's disease)、注意力缺乏症(ADD)、注意力不足過動症(ADHD)、精神病、睡眠失調、肥胖症、頭暈、癲癇症、動暈症、呼吸道疾病、過敏、過敏誘發之氣管反應、過敏性鼻炎、鼻充血、過敏性充血、充血、低血壓、心血管疾病、胃腸道疾病、胃腸道之蠕動過度或過低及酸分泌，其包含投與其治療有效量。
