Provided herein are solid dispersions comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and a polymer and solid forms comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and a coformer. Pharmaceutical compositions comprising the solid dispersions and solid forms (e.g., cocrystals) and methods for treating, preventing and managing various disorders are also disclosed.Linvention concerne des dispersions solides comprenant du 4-amino-2-(2,6-dioxopipéridine-3-yl)isoindoline-1,3-dione et un polymère, et des formes solides comprenant le 4-amino-2-(2,6-dioxopipéridine-3-yl)isoindoline-1,3-dione et un co-formeur. Linvention concerne également des compositions pharmaceutiques comprenant les dispersions solides et les formes solides (par exemple des co-cristaux), ainsi que des méthodes pour traiter, prévenir et gérer diverses affections.