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SOLID DISPERSIONS AND SOLID FORMS COMPRISING 4-AMINO-2-(2,6-DIOXOPIPERIDINE-3-YL)ISOINDOLINE-1,3-DIONE, METHOD OF PREPARATION AND USE THEREOF
专利权人:
CELGENE CORPORATION
发明人:
FRANK, Anthony,MENON, Anil
申请号:
USUS2017/041715
公开号:
WO2018/013689A1
申请日:
2017.07.12
申请国别(地区):
WO
年份:
2018
代理人:
摘要:
Provided herein are solid dispersions comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and a polymer and solid forms comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and a coformer. Pharmaceutical compositions comprising the solid dispersions and solid forms (e.g., cocrystals) and methods for treating, preventing and managing various disorders are also disclosed.Linvention concerne des dispersions solides comprenant du 4-amino-2-(2,6-dioxopipéridine-3-yl)isoindoline-1,3-dione et un polymère, et des formes solides comprenant le 4-amino-2-(2,6-dioxopipéridine-3-yl)isoindoline-1,3-dione et un co-formeur. Linvention concerne également des compositions pharmaceutiques comprenant les dispersions solides et les formes solides (par exemple des co-cristaux), ainsi que des méthodes pour traiter, prévenir et gérer diverses affections.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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