Koncarevic, Alan,Lachey, Jennifer,Seehra, Jasbir,Sherman, Matthew L.
申请号:
AU2019206030
公开号:
AU2019206030A1
申请日:
2019.07.17
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
#$%^&*AU2019206030A120190808.pdf#####ABSTRACT In certain aspects, the present invention provides compositions and methods for treating 5 fatty liver disease by administering an antagonist of an ActRIIB signaling pathway. Examples of such antagonists include ActRIIB polypeptides, anti-ActRIIB antibodies, anti-myostatin antibodies, anti-GDF3 antibodies and anti-activin A or B antibodies. A variety of hepatic and metabolic disorders may be improved by treating fatty liver disease.