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Osteoarthritis treatment
专利权人:
The University of Melbourne
发明人:
HAMILTON, John Allan,COOK, Andrew David
申请号:
AU2015224416
公开号:
AU2015224416A1
申请日:
2015.09.09
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
#$%^&*AU2015224416A120151001.pdf#####H:\aar\Interwoven\NRPortbl\DCC\AAR\8378984_1 .DOC-04.09.2015 - 34 ABSTRACT The present invention relates generally to a method for the treatment and/or prophylaxis of osteoarthritis (OA). In accordance with the present invention, an antagonist of GM-CSF can be effective in the treatment of osteoarthritis. An antagonist of GM-CSF includes, but is not limited to, an antibody that is specific for GM-CSF or the GM-CSF receptor. The present invention further provides transgenic animals, such as a GM-CSF knock-out mouse, useful for testing antagonists in certain disease models.
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