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4(フェニル-ピペラジニル-メチル)ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用
专利权人:
アストラゼネカ・アクチエボラーグ
发明人:
ウィリアム・ブラウン,クリストファー・ウォルポール,ニクラース・プローベック
申请号:
JP2010002450
公开号:
JP5028500B2
申请日:
2010.01.08
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
Compounds of general formula I R 1 is selected from any one of phenyl, furanyl, and pyrrolyl, wherein each of phenyl, pyrrolyl, and furanyl may optionally and independently be substituted by 1 or 2 substituents selected from CF 3 , methyl, chloro, fluoro, bromo, and iodo R 2 is independently selected from ethyl and isopropyl R 3 is independently selected from hydrogen and fluoro and R 4 is -NH 2 or salts thereof or separate enantiomers and salts thereof are disclosed and claimed in the present application, as well as separate enantiomers of the compounds and salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain, anxiety and functional gastrointestinal disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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